Help Scientists in Their Search for a Cure Download Folding@home and band together with people across the globe by adding the massive compute power of a NVIDIA® GeForce® GPU to one of the largest supercomputers in the world. Use your PC to help fight many of the world’s most devastating diseases while you sleep at night.* Use your NVIDIA GPU to enable scientific research faster than ever before. * 100 times faster than average Windows PC (CPU only)* * 30 times faster than average Mac OS X/Intel PC (CPU only)* *Calculated based on the average FLOPS reported for active clients at the Folding at Home client statistics page as of February 19, 2009. What is Folding@Home? The Folding@Home goal is to understand protein folding, protein aggregation, and related diseases What are proteins and why do they "fold"? Proteins are biology's workhorses -- its "nanomachines." Before proteins can carry out their biochemical function, they remarkably assemble themselves, or "fold." The process of protein folding, while critical and fundamental to virtually all of biology, remains a mystery. Moreover, perhaps not surprisingly, when proteins do not fold correctly (i.e. "misfold"), there can be serious effects, including many well known diseases, such as Alzheimer's, Mad Cow (BSE), CJD, ALS, and Parkinson's disease. What does Folding@Home do? Folding@Home is a distributed computing project which studies protein folding, misfolding, aggregation, and related diseases. We use novel computational methods and large scale distributed computing, to simulate timescales thousands to millions of times longer than previously achieved. This has allowed us to simulate folding for the first time, and to now direct our approach to examine folding related disease. How can you help? You can help our project by downloading and running our client software. Our algorithms are designed such that for every computer that joins the project, we get a commensurate increase in simulation speed. RECOMMENDED SYSTEM REQUIREMENTS: CUDA enabled GPU (NVIDIA GeForce 8-series or later) 256 MB RAM, 1 GB or higher recommended PCI Express or PCI Express 2.0 compliant motherboard Microsoft Windows Vista, 32-bit or 64-bit, Windows XP or Windows XP Professional ×64 Edition 50 MB of available hard disk space Latest NVIDIA Driver *Please Note: The NVIDIA Folding client is a High Performance client. Although it runs in the background, it uses some compute resources. Depending on the PC and applications you use, you may find it best to run it only when you aren’t using your PC.